A sensitive HPLC–MS/MS method for the determination of dolutegravir in human plasma
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A rapid and sensitive HPLC-Fluorescence method for determination of Mirtazapine and its two major metabolites in human plasma
A rapid and sensitive HPLC method has been developed for the quantification of mirtazapine (MRZ), a noradrenergic and specific serotonergic inhibitor antidepressant (NaSSA) and its two major metabolites N-desmethylmirtazapine (NDM) and 8-hydroxymirtazapine (8-OHM) in human plasma. The separation was achieved using Chromolith C18 column and a mobile phase of acetonitrile: phosphate buffer (pH=3,...
متن کاملA rapid and sensitive HPLC-Fluorescence method for determination of Mirtazapine and its two major metabolites in human plasma
A rapid and sensitive HPLC method has been developed for the quantification of mirtazapine (MRZ), a noradrenergic and specific serotonergic inhibitor antidepressant (NaSSA) and its two major metabolites N-desmethylmirtazapine (NDM) and 8-hydroxymirtazapine (8-OHM) in human plasma. The separation was achieved using Chromolith C18 column and a mobile phase of acetonitrile: phosphate buffer (pH=3,...
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Phenylalanine (Phe) is the most reliable indicator for the diagnosis of phenylketonuria (PKU). The purpose of this study is to establish a reliable and quick method for the assignment of Phe in peripheral capillary blood from newborns and children by high performance liquid chromatography with ultraviolet detection (HPLC-UV). PKU is an inborn error of metabolism characterized by the inability o...
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ژورنال
عنوان ژورنال: Journal of Chromatography B
سال: 2014
ISSN: 1570-0232
DOI: 10.1016/j.jchromb.2013.11.054